We can see Stephen Strange working as the court magician of Queen Elizabeth, and Nick Fury acting as the Queen's spymaster (ala 007). Both Strange and Fury are working against the political maneuvering of Count Otto von Doom.
The two groups are seeking for the fabled treasure of the knights templar. Fury and Strange get to meet (and work with) other Marvel heroes: like the minstrel Matthew Murdoch (Daredevil), Peter Parquagh (Spiderman), Carlos Javier and his witchbreed (Professor X and the X Men), and the Four survivors of the Fantastick ship.
I like the way Giaman integrated the Marvel heroes into a Elizabethan-like setting. The plot invokes a sense of mystery and urgency. What is the legendary treasure of the Knight's templar? Who is Virginia Dare and his white American Indian bodyguard Rojhaz?
Overall, I find the series a nice read. It's been a long time since I enjoyed reading a comic book with an excellent storyline. I'm planning to buy the next series of the 1602 series (where some of the heroes have arrived in the New World).